Hematology & Oncology Testing from Quest Diagnostics

Leumeta™ cancer tests use blood plasma instead of bone marrow for diagnosis and monitoring of leukemia and lymphoma

The new Leumeta™ cancer tests are now available and may, in the future, provide an alternative to painful bone marrow biopsies for the nearly one million Americans battling or recovering from leukemia and lymphoma. Learn more.

As the world's leading provider of diagnostic testing, information and services, Quest Diagnostics developed Leumeta cancer tests to identify and analyze genetic components of leukemia and lymphoma tumors using blood plasma instead of bone marrow. The assays are designed to measure tumor load, or the amount of cancer in a patient; detect certain blood cancer markers; and assist the physician in monitoring the impact of treatment. They are the first diagnostic assays available to doctors that directly measure tumor load and identify markers in blood plasma.

Leumeta assays have the potential to help doctors personalize the way they practice medicine by providing information about the status of leukemia and lymphoma in blood plasma to help the physician determine the treatment that works best for each patient, based on the specifics of that patient's cancer and other clinical information available to the physician. Although more prospective studies are needed, sample collection for these blood plasma assays developed from this technology will meanwhile be less painful and more convenient than for bone marrow tests, while offering doctors a new tool to assess the status of these cancers.

A Full Hematology and Oncology Test Menu including:

Hematologic Malignancies

Comprehensive hematopathology services, including:
Morphologic evaluation
Immunohistochemistry
Multiparametric Flow Cytometry
Cytogenetics and FISH
Molecular Pathology (DNA/RNA Studies)
Cell Sorting
Minimal residual disease monitoring
Unsurpassed hematopathology menu including new tests such as:
IgVH gene mutation status
ZAP 70
FLT-3
Leumeta™ Plasma-based assays (for Leukemia and Lymphoma)
FIP1L1-PDGFRA gene rearrangement
Convenient CLL Prognostic Panels with integrated interpretation
Image reports include integrated interpretation
Bone Marrow Aspiration and Biopsy Sample Report
Leukemia / Lymphoma Evaluation by Flow Cytometry Sample Report
Hematopathology-specific requisitions and specimen collection kits assist ordering
Easy access to board-certified hematopathologists for consultation on difficult cases
Extensive coagulation menu with dedicated coagulation experts available 24/7 for clinical consultation at Quest Diagnostics Nichols Institute, San Juan Capistrano
Extensive participation in clinical trials

Oncology

Extensive menu and pioneers in over 29 oncology assays. Some new assays include:
UGT1A1
Epidermal Growth Factor Receptor (EGFR)
Urokinase plasminogen activator (uPA) and Plasminogen activator inhibitor-1 (PAI-1)
TA90 Immune Complex
Microsatellite Instability
MLH1, MSH2, and MSH6 gene mutations for Hereditary Non-Polyposis Colorectal Cancer (HNPCC)
CellSearch™' Circulating Tumor Cell Test
Biotechnology and academic partnerships offer new diagnostic assays
Extensive participation in clinical trials

Access and Convenience
A national network of laboratories with locations in or near all major cities and esoteric testing laboratories on both coasts.
Convenient specimen collection options, including courier services and more than 2,000 conveniently located patient service centers across the country
Relationships with most third-party payors and purchasing group organizations
Hematology & Oncology Center hotline for direct access to trained personnel: 1-800-Nichols, ext. 2906

Online Resources for Healthcare Professionals
Obtain test ordering codes and specimen requirements from our online Test Menu
Learn about Hematology and Oncology test selection, utilization, and interpretation in our Interpretive Guide
Simplify test ordering and results reporting with Care360

Online Test Information for your Patients

Your patients can learn about health conditions and laboratory tests in our online Patient Health Library. The library is founded on evidence-based information, and includes topics such as

Healthwise Self-Care Checklist
Making Wise Health Decisions
Work in Partnership with Your Doctor

Contact a Quest Diagnostics Sales Representative for More Information
Contact a sales representative to learn more about our testing services or to become a Quest Diagnostics client.

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